Mission Bio

Mission Bio is helping researchers and clinicians unlock single-cell biology to enable the discovery, development, and delivery of precision medicine. Mission Bio’s Tapestri Platform is the only system capable of simultaneously providing both genotype and phenotype data from the same cell, across thousands of single cells. With DNA as a foundation, MB’s proprietary two-step microfluidic workflow enables the simultaneous detection of analytes, including SNVs, CNVs, and proteins. The Tapestri single-cell DNA panels and protein panels are highly sensitive and customizable panels that enable true multi-omics analysis for identifying co-mutation patterns and zygosity in subclones, or cellular identities and subtle cell states and are applied across a wide range of discovery and translational research applications. Meet the complexity of cancer with true multi-omics analysis.

The Tapestri Platform: An end-to-end workflow from sample preparation to visualization with publication-ready insights for single-cell analysis.

The Tapestri is the only system capable of simultaneously providing both genotype and phenotype data from the same cell, across thousands of single cells. With DNA as a foundation, our proprietary two-step microfluidic workflow enables the simultaneous detection of analytes, including SNVs, CNVs, and proteins. Meet the complexity of cancer with true multi-omics analysis.

 

 

Tapestri single-cell DNA panels and protein panels are targeted panels providing focus on key regions of interest for efficient use of sequencing budget and analysis time.  These are highly sensitive and customizable panels that enable true multi-omics analysis on the Tapestri Platform. Whether identifying co-mutation patterns and zygosity in subclones, or cellular identities and subtle cell states, Tapestri single-cell DNA panels and protein panels can be applied across a wide range of discovery and translational research applications.

Hematology Panels

Clonal evolution is foundational to disease progression in hematologic malignancies, which can impact therapy response, resistance, relapse, and residual disease. Tapestri single-cell hematology panels provide insight into disease drivers and mutation patterns missed during bulk sequencing. By interrogating clonal architecture, rare subclones associated with remission and therapeutic resistance can be identified.

Solid Tumor Panels

Cellular heterogeneity in solid tumor cancers impacts clonal evolution and patient outcomes. Single-cell DNA solid tumor profiling enables high resolution of the genomic diversity in a variety of tumor types by interrogating specific regions in oncogenes and tumor suppressors.

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