Bioskryb has ushered in a whole new era of single-cell whole genome amplification. The benefits of the BioSkryb ResolveDNA® technology include the ability to control the amplicon size during amplification. This allows the incorporation of barcode identifiers into each sample template, enabling unparalleled reproducibility and sensitive detection of DNA lesions. The complete workflow solution is especially useful in cancer research as it allows the detection of single resistant mutant cells (MRD) in heterogeneous cancers such as leukemia. It also enables new applications for gene sequencing that need a level of resolution simply not available today.
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Inventia develop solutions to create advanced cell models and help forward-thinking pioneers in the fields of drug discovery and biomedical research to create human tissue for research and therapy.
Inventia’s systems create advanced cell models which most closely and predictably imitate real human tissue structure and behaviour across a range of disease states. This physiological complexity offers an environment in which world-class research and discovery can occur, right in your own lab.
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Unchained Labs is committed to provide products that will make a real difference in the research that scientists do every day. They offer solutions for biologics such as screening for stability and aggregation, measuring concentration, buffer exchange and clean up. These capabilities have been further applied to cell and gene therapy workflow by including solutions for viruses and nanoparticles with DNA or RNA.
Uncle is their All-In-One Biologics Stability Platform. UNcle can make multiple measurements from the same sample, combining fluorescence, SLS and DLS reads in one machine. This allows researchers to quickly and efficiently characterize all the size, aggregation, thermal ramp, isothermal and viscosity information in as many as 48 protein constructs and formation simultaneously.
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Parse Biosciences Inc., based in Seattle WA, is providing researchers with the ability to perform single cell sequencing with unprecedented scale and ease. This latest innovation in single cell genomics allows for unprecedented scale without the limitations of microfluidic droplet-based approaches.
Single cell sequencing has already enabled ground-breaking discoveries which have led to new understandings of cancer treatment, tissue repair, stem cell therapy, kidney and liver disease, brain development, and the immune system. Parse Biosciences has introduced pioneering technology using combinatorial cDNA barcoding within cells themselves, without a need for cell partitioning instruments. Demonstrating the clear ability to scale, Parse Bio has recently introduced their Evercode Mega Assay for uniquely coding up to a million cells per sample.
LevitasBio has developed the first truly novel approach to cellular analysis in 30 years with a powerful method of cellular analysis. This label-free magnetic levitation technology enables researchers to rescue and achieve higher quality and quantity of cells without introducing bias, high pressure, and modifications to gene expression profiles, thus ensuring the integrity of downstream data and analysis.
Using Magnetic Levitation Technology, LevitasBio’s instruments and assay kits leverage the power of levitation to accurately detect, quantify, enrich and test cells. This label-free unbiased and gentle technique requires minimal time and handling, creating a truly game-changing tool for advancing the fields of Immunology, Oncology, Stem Cells, Large Cell/ Organoid, Single Cell Sequencing, Bacteriology Infectious diseases and more.
Cell Signaling Technology is a private company founded by scientists and dedicated to providing high quality research tools to the biomedical research community. CST develops and produces antibodies, ELISA kits, ChIP kits, proteomic kits, and other related reagents used to study the cell signaling pathways that impact human health. Well known for their mission to produce in-house and rigorously validate every product they make to assure dependable performance – CST are adamant about making the highest quality, most consistent antibodies that work the first time, and every time. All CST antibodies go thru in-house Antibody validation, application testing, optimized target selection and are provided together with a performance guarantee and dilution and optimization protocols.
CST maintains an in-house research program, particularly in the area of cancer research, and has published scientific papers in many peer-reviewed journals. In addition to product development and production, CST is also involved in the development of new technologies for signaling analysis as well as mechanistic cell biology research, particularly in the field of cancer research. CST also curates and maintains PhosphoSitePlus, a web-based bioinformatics resource that details post-translational modifications (PTMs) in human, mouse and rat proteins.
Twist Bioscience has revolutionized synthetic DNA manufacturing by developing a silicon-based DNA Synthesis Platform to address the limitations of throughput, scalability and cost inherent in legacy DNA synthesis methods. Applying rigorous engineering and AI principles to harness the highly scalable production allowing semiconductor level precision in manufacturing DNA at scale. Twist has industrialized the production of cost-effective, high-fidelity, high-throughput DNA, for a range of NGS panels, Genes, Oligo Pools, Custom Libraries and Variant Libraries, all tailored precisely for your experiment.
ProteinTech is the benchmark for manufacturing original antibodies. With an emphasis on developing antibodies from whole proteins, ProteinTech provides researchers with unmatched reliability and reproducibility. Founded by scientists in 2001 after their continued frustration with failed experiments due to low-grade antibodies, ProteinTech is on a path to foster better science by producing the highest quality antibodies for every human protein.
ChromoTek, now a part of Proteintech inc., pioneered the development and commercialization of Nanobody-based research reagents. They are the global market and product leader for high quality and reliable Nanobody-based reagents, which assist our customers’ research. In addition, ChromoTek is a trusted service provider of custom-made Nanobodies for the pharmaceutical industry.
Axel Semrau Has been active for more than 35 years in the development, distribution and support for the automation of sample preparation and chromatography, chemical synthesis as well as application optimized workstations. AS develops its own hardware and software in order to be able to provide unique and robust solutions in chromatography providing total solution, application based lab automation sample prep and analysis systems for application such as Mineral oils (MOSH/MOAH), PAHs, Sterols, and Glyphosate in Foods, as well as protein extraction, Fatty Acid Methyl Esters (FAME) and more.
BioTek Instruments is a global leader in microplate instrumentation, cell imaging systems, software and automation used to aid in the advancement of life science research. BioTek offers multi-mode, luminescence, and absorbance readers; microplate washers and dispensers, stackers and pipetting systems as well as their renowned Gen5 data analysis software. BioTek’s has been the leading innovator of plate-based cell imaging with the intro of their Cytation range of imaging systems as well the BioSpa live cell imager and Lionheart automated microscope.
Applied Biosystems (Formerly Affymetrix, and part of Thermo Fisher Scientific) GeneChip products, tools, and resources help advance the work of researchers via microarray analysis. Application areas include plant and animal genomics and transcriptomics, including basic research, technologies for breeding, population diversity and conservation, trait analysis, cancer research and clinical validation and cytogenetics. The genetics of human complex traits, Mendelian disorders, and disease states are studied across population using high density genotyping arrays for genome wide association studies.
CTC Analytics is a Swiss company at the forefront of automation for gas and liquid chromatography with their PAL System series of lab automation systems and with over 30 years of continuous development and improvement. This flexible, highly reliable, advanced laboratory sample handling platform is widely adopted in the pharmaceutical, life science, chemical, environmental and food & flavor industries. The PAL Systems robotic systems have a flexible modular design, allowing the worldwide customer base to create their own customized solution to respond to their individual needs to increase productivity, accuracy, reliability and traceability.
Seahorse Bioscience, now part of Agilent, is known for their XF Analyzers used to measure oxygen consumption rate (OCR) and extracellular acidification rate (ECAR) of live cells in a multi-well plate, interrogating key cellular functions such as mitochondrial respiration and glycolysis. XF Analyzers perform compound addition and mixing, label-free analytical detection, and automatic measurement of OCR and ECAR in real time. Also under Seahorse are the MiToXpress and pH-Xtra plate reader assays, easy to use kits for measuring real-time energy flux, mitochondrial function, glycolysis and substrate utilization in living cells, isolated mitochondria, 3D cultures, and microbes.
BIOER, with origins in pioneering and manufacturing precision Peltier cooling systems, now design and produce some of the finest and most durable Peltier based instruments for life science research. In 1998, Bioer launched China’s first semiconductor-based (Peltier) PCR system. Bioer is the leading manufacturer of PCR systems in China, offering some of the world’s finest thermal cyclers for PCR and Real Time PCR, as well water baths, Dry Baths, NA Extraction, and a range of quality genomic and kits.
Mission Bio is helping researchers and clinicians unlock single-cell biology to enable the discovery, development, and delivery of precision medicine. Mission Bio’s Tapestri Platform is the only system capable of simultaneously providing both genotype and phenotype data from the same cell, across thousands of single cells. With DNA as a foundation, MB’s proprietary two-step microfluidic workflow enables the simultaneous detection of analytes, including SNVs, CNVs, and proteins. The Tapestri single-cell DNA panels and protein panels are highly sensitive and customizable panels that enable true multi-omics analysis for identifying co-mutation patterns and zygosity in subclones, or cellular identities and subtle cell states and are applied across a wide range of discovery and translational research applications. Meet the complexity of cancer with true multi-omics analysis.
Cytiva is a global provider of technologies and services that advance and accelerate the development and manufacture of therapeutics. Formerly part of GE Healthcare Life Sciences, we have a rich heritage tracing back hundreds of years, and a fresh beginning since 2020. Cytiva customers undertake life-saving activities ranging from fundamental biological research to developing innovative vaccines, biologic drugs, and novel cell and gene therapies. Cytiva is a 3.3 billion USD global life sciences leader with over 7000 dedicated associates across 40 sites providing leading products including the Hyclone brand of cell culture products, Akta range of protein purification solutions, Biacore protein interaction analysis, as well as a full range of Western Blot and Genomics reagents, Gel Imaging systems, High Content Screening instruments, and much more.
Sage Science develops products to improve sample preparation workflows for genomic sequencing (NGS) and protein analysis. Sage Science developed the Pippin Prep and BluePippin preparative electrophoresis systems for targeted size selection of biomolecules. The Pippin platform has since established itself as a key platform for the construction of high-quality libraries for next-generation sequencing. In 2014, Sage Science released a new electrophoresis platform, the SageELF, for whole sample fractionation of DNA or proteins, and the PippinHT. Sage Science products are acknowledged as a critical and standard part of most NGS workflows.
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MetaSystems specializes in automated scanning and imaging for cytogenetics, cancer genetics, toxicology, pathology, forensic sciences, and other applications. Founded in 1986, the company started with the development of an automatic metaphase finding system. Since the introduction of the karyotyping system Ikaros in 1991, MetaSystems grew dynamically to be the leading supplier of automated imaging solutions in the field of cytogenetics. Metasystems also offer a full range of FISH probes quickly gaining recognition worldwide.
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Quanterix has developed an ultra-sensitive diagnostic platform capable of measuring individual proteins at concentrations 1000 times lower than the best immunoassays available today. The Single Molecule Array (Simoa™) technology at the heart of the platform enables the detection and quantification of biomarkers previously difficult or impossible to measure, opening up new applications to address significant unmet needs in life science research, in-vitro diagnostics, companion diagnostics, blood screening, and more. Quanterix is the exclusive licensee of a broad intellectual property portfolio initially developed at Tufts University by Dr. David Walt, scientific founder of Quanterix and Illumina.
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Fluxion Biosciences was founded in 2005 in San Francisco, California in the USA with its principal focus on analytical instruments for functional cellular analyses. In 2008, BioFlux 200 was the recipient of the R&D 100 Award given by R&D Magazine to the top 100 new technologies of the year. In 2010 and 2013, Fluxion received additional R&D 100 awards for the IonFlux HT System and IsoFlux System, respectively. In addition to its core product lines, Fluxion is also engaged in cutting-edge research to produce the next generation of breakthrough technologies.
At Research Instruments, we are committed to facilitating access to state of the art research tools by continually introducing new technologies and providing complete solutions to the scientific community while constantly challenging existing processes. We are dedicated to being a vital source for scientific research, our leading-edge solutions give our clients access to faster and efficient opportunities, enabling them to achieve more from their operations while exceeding their requirements. The passion, resourcefulness, and creativity of our employees are the driving force behind our success on a regional scale, enabling us to create sustainable value in the scientific industry today.
Horizon Discovery is a world-leading gene editing company that designs and engineers genetically-modified cells and then applies them in research and clinical applications that advance human health. Horizon’s core capabilities are built around its proprietary translational genomics platform, a highly precise and flexible suite of gene editing tools (rAAV, ZFN, and CRISPR) able to alter almost any gene sequence in human or mammalian cell lines. Horizon offers over 23,000 catalogue products and related research services, almost all of which are based on the generation and application of cell and animal models that accurately recapitulate the disease-causing genetic anomalies found in diseases like cancer.
Dharmacon, now a part of Horizon, and a leader in custom RNA synthesis, was an early player in the field of RNA interference, contributing several key scientific findings and some of the first commercially siRNA reagents. Today, their areas of research and research tools have expanded to support all aspects of RNAi interference; siRNA, lentiviral shRNA, tools for microRNA research and genome-scale libraries for RNAi functional screens of genes, microRNAs and long non-coding RNAs. For over-expression, Dharmacon has one of the largest collections of cDNAs and ORFs commercially available.
CODEX DNA, Inc., Formerly known as SGI-DNA, and founded by Dan Gibson — the creator of the industry-standard Gibson Assembly® methodology, CODEX offers Synthetic DNA on demand. CODEX is on a mission to empower scientific researchers to rapidly and accurately write large quantities of synthetic genes. To, in effect, build biology. CODEX is decentralizing DNA synthesis with the world's most innovative portfolio of synthetic biology platform technologies. Their gene synthesis portfolio reduces the turnaround time for synthesizing biology workflows from weeks and months down to days and hours and includes the BioXp™ 3200 system (the world's first and only gene printer), variant library services, and Gibson Assembly® reagents. In addition to automating, speeding, and optimizing DNA design and synthesis, CODEX and the BioXp™ system ensure your designs stay in your hands, marrying speed and security for innovators in drug discovery, vaccine development, DNA data storage, and beyond.
BioCision, makers of the CoolBox, Coolcell and more, make products designed to improve standardization and eliminate variability in temperature-sensitive sample handling, storage, and transport. BioCision products are now the top choice for biomedical research and manufacturing teams that require standards in precision, consistency, and reproducibility. The intuitive design and interconnectivity of BioCision products enable a new standard of integrity of temperature-sensitive therapeutics, biological samples, and biomaterials.
iNtRON Biotechnology is a global biotechnology company with a complete Bio-Value Chain for diagnosis, prevention, and treatment. They are a premier manufacturer of molecular biology reagents and kits in the international market which has been used worldwide. Products include DNA prep kits, RNA prep kits, PCR premix, transcription and translation kits, Western Blot detection reagents, and protein extraction kits.
NanoEnTek develops innovative products of life science research and point-of-care diagnostics. Lab-on-a-chip. The first successful product was Countess, the world’s first personal cell counter. Then, JuLI, a live cell viewer breaks the space restrictions and realizes lab-free life for bio researchers by WiFi remote control. NanoEnTek offers a range of cell counting systems and cell imagers, chip-based IVD systems, as well as their C-chip disposable Hemocytometer.
biocrates is the global leader in mass spectrometry-based quantitative metabolite analysis. With more than 20 years of experience, biocrates metabolomics kit technology has been applied for thousands of publications and by hundreds of clients in pharma, academia and health institutions. biocrates has succeeded in building a global community of more than 100 core facilities, CROs, service customers & kit users to accelerate science using quantitative metabolomics.